Relationship between Domain-Specific and Broad Cognitive Intra-Individual
Variability and Functional Abilities
 
   Lead Investigator:    Channing Sofko
   Institution      :    University of South Alabama
   E-Mail           :    csofko@gmail.com
   Proposal ID      :    436


   Publications:


1  Sofko C
   Neuropsychological Intra-Individual Variability and Resilient Cognitive Aging
   2017   Dissertation  University of South Alabama , 

   DEFENDED





   Proposal Description:
   We request to use the NACC database to examine the relationship between cognitive intra-individual variability, neurofibrillary degeneration, and functional abilities further we wish to examine the effect of domain-specific variability versus broad variability.  Our group has previously examined          cognitive dispersion in traumatic brain injury (TBI). We found that TBI severity as measured by loss of consciousness had a strong linear relationship with increasing cognitive intra-individual variability and increased variability was associated with decreased overall cognitive performance.  We would like to use the NACC neuropsychological data to calculate an overall test battery mean (OTBM) for each individual and use the standard deviation around this mean as an index of intra-individual variability. We then propose to examine how intra-individual variability is related to functional abilities at different time points.  We also propose to examine broad intra-individual variability versus domain-specific variability.